The Leading Cause of Death Worldwide

Cardiovascular disease (CVD) is the leading cause of death globally, accounting for 25% of deaths in the U.S. and 31% of deaths worldwide. Nearly 18 million people die each year from cardiovascular disease (CVD)-related events including myocardial infarction (MI).

Despite current standard of care treatments, residual risk of MI, stroke and death remains high in patients with CVD. Developing new treatments is a challenge due to the heterogeneity of the patient population and the resulting variation in response to treatment.

Scientific advances in precision medicine now allow for a patient’s genetic profile to be considered during the development of new treatments. This targeted approach identifies individual patients who may benefit from a particular treatment, based on a specific genetic subtype.

DalCor is developing dalcetrapib, the first precision medicine aiming to reduce fatal and non-fatal MI above and beyond the current standard of care in patients who carry the ADCY9 rs1967309 AA genotype.